Had a little time to go over the matchups before I snooze. My picks: Marquette/OSU/Michigan/Louisville. Marquette just wins games, there's not really much else to say there. And they won the only meeting between the two this year. I think Wichita keeps it close, but Ohio's probably too athletic for the Shockers. I'll be rooting for the upset, though. Michigan matches up really well with Florida - I like Patric Young, but you won't have to worry about driving inside and meeting the nation's best shot blocker like tonight. Also, Michigan's backcourt advantage, Trey Burke being Trey Burke, etc. Louisville is just balling right now. It's hard for me to see a scenario in which they aren't the national champion.
EDIT: Just remembered the dome effect discussed earlier. 40% of Florida's field goal attempts are threes, so there's that.