Louisville has the easiest road to a BCS title game I ever seen.
They have an easy road to an undefeated season, but they don't control their own destiny to the BCS title game.
At minimum, if there are 2 undefeated teams from any of the big 5 conferences, or if there is 1 undefeated team + a 1-loss SEC champion, then Louisville won't be in the BCS title game. And they might still need an average margin of victory of 30-40 points to be in ahead of a 1-loss champ from other conferences.