Lol what. Lincoln is as big as Knoxville and Eugene is a major metropolitan city that is home to a few Fortune 500 companies like Nike.
I don't know about Oregon, but I can attest to the Nebraska part. I drove to Omaha for UT's first game in CWS, and those states are sparse. If you look it up, Lincoln has metro population of 302k while Knoxville has a metro population of 800k+. However, Omaha is a little less than a hour from Lincoln and has about a million.