Every person formerly seeking the nomination will have said bad things about the actual nominee, but some of hers, as I recall, were really harsh and would seem likely to fall into the "no take backsies" realm.
Prediction: The Democrat Party will begin their attempt to act and speak in a more unifying manner by telling the country that Vance is Satans Spawn, and that if he were to step in for Trump for whatever reason, he will throw all colored people in concentration camps and kill all the gays.
A lot of people say that the VP has no bearing on the election. Normally, I would agree, but given Trump's age, I think the VP candidate is uniquely important. This could actually hurt Trump in the general.