Now, this is basketball and not darts, but anyone who has ever thrown darts at a high level understands how an interruption in flow in the middle of a good run can quickly change results.
Once you throw that first dart and it goes into the bullseye, you don't stop and high-five, or take a sip of your beer, or even change your gaze. Bull goes in and you immediately throw the next two in the exact same motion and focus, greatly increasing the likelihood that all three darts will be winners.
If that flow is interrupted after that first bullseye, chances of coming back around into that exact same focus after that "time out" is greatly reduced.
In my opinion, basketball teams can experience a type of success-driven adrenaline rush that can suddenly bring them into sharp focus, and their body movements can become more self-assured, and they can begin to experience the game in a kind of surreal, euphoric way. This is, IMO, exactly what "going on a run" means.
And as a person who has played darts AND basketball, this is why I think time outs are ABSOLUTELY a weapon that, more often than not, would be wise to use against most opponents who get into an adrenaline groove. You have got to at least try to interrupt that chemical flow!!!!!! You've got to try to get opponents' brains to stop sending "I can, and I WILL, do everything right" signals to their bodies. Make the opponent go to the sideline for a couple of minutes, and maybe that'll be just enough time for a memory of some bad game from the past to pop in there ... or that exam you have tomorrow ... or, whatever.
I have long advocated for shooting free throws without interruption as well. If that first one goes in, IMMEDIATELY get the ball and shoot the second one while in that same head/body space. Skip the interruption of the hand-slaps. Everyone just stay where they are and let the shooter stay focused. That's what I would do with my team if I were the coach.