Stats do not a game make. I believe that the Lady Vols are in an us versus the world situation. No one gives them a chance, but stats are not a measurement of heart and desire. I believe that the Lady Vols will play better individually without Izzy because they no longer have their major go to star. It is now every player's responsibility to step up their game and I believe they will.
You're right, stats don't make up all of the equation. Other major factors will play their roles in how each prepares and competes in this game:
#1) The SEC Regular-Season Title: both UT and USC being undefeated in conference play places them easily above the rest of the league in vying for the reg. season title. A loss either way would make the team with the short end of the stick finish out of the running. IMO after USC the Lady Vols don't really have much left in-conference to challenge them: they will go to UGA and then host Vanderbilt, 2 teams that for at least half the SEC season has been struggling. IMO UT should wade through those 2 teams.
USC on the other hand will host and then go to top-15 teams Miss State and UK. These are still pretty tough opponents who are trying to position themselves for NCAAT seeding. And while there's no 3rd-place team that's in position to make a run at the reg. season SEC title, a loss to one of those teams by USC could mean they still end the season tied with UT if they beat UT, or finish out of the running for the title if they lose to UT. I don't know if there'd be co-regular-season champs, or if USC would be the lone champs based on winning the head-to-head tiebreaker, should they lose to either MSU or UK. Of course I'm sure the USC team is expecting to beat everyone and make the issue a moot one, but solution #1 is certainly to beat UT. While UT needs to beat USC, and they are in the drivers seat to the finish...
#2) NCAAT #1 Seeding: There are currently about 6 teams that are in the late discussions for #1 seeds for the NCAAT - UConn, USC, Baylor, Notre Dame, Maryland, & Tennessee. One could make the argument that Oregon State makes it 7 teams. Most opinions of course have UConn etched in granite as a recipient, and USC right behind them, then the rest in a mix-discussion where either has as much argument to garner one over the other.
Should UT lose to USC, they could fall below the others in consideration and end up as a 2-seed. While if USC loses to UT, it falls into the mix with the others. That mix is a dangerous one, and there will be 2-4 teams that end up a 2-seed that had as much argument for a 1-seed as 2-3 of the 4 that get them. USC wants to remain above that mire by beating UT, but then they also have to worry about their games with MSU and UK. UT wants to remain either in front of or even rise above that pack and give themselves more assurance of getting a #1 seed. So this game has substantial seeding ramifications for each team.
#3) Establishing Program Positions: Both teams have some program questions to answer - is UT still among the elite programs of the nation as it's been for decades now, and is USC rising to include itself among them. Both have struggled to find answers: UT beating top-10 opponents on the road since LSU in '07-'08, USC beating enough top-10 opponents, regardless of home or away. A win by either would help boost the program where it wants to be. UT is still regarded by the SEC as the standard to strive to, and USC knows it won't legitimize itself as a new league power unless it beats UT more often. UT on the other hand doesn't expect to step aside, and beating USC would be a clear signal that it's still the Queen of the mountain in the SEC.