Latest Coronavirus - Yikes

[volfanhill]

The most vaccine-hesitant group of all? PhDs - The Post

 

[WoodsmanVol]

Link for those who actually want to learn something: Common myths about Covid – debunked

 

[Boston Vol]

They really are terrified of this dude

 

[UT_VOLS13]

They really are terrified of this dude

LOL, Howard Dean calling someone an embasassment.

 

[evillawyer]

Because you are missing a couple of very important numbers:

1) there is most certainly some level of background immunity, as has also been discussed ad nauseum. Common knowledge now. That means that likely 40-60+% of people are not susceptible to infection.

2) a large percentage of people are infected and never know it, proven conclusively by antibody studies. In many early studies, the seroconversion rate was 5-10x the known positive/PCR rate. This does two things: reduces the true mortality by a decimal point (prob around 0.1%) and reduces the threshold of "known" positives (relative to the overall/unknown/asymptomatic) required to get to HIT.

WHAT DOES THIS LOOK LIKE IN THE REAL WORLD? In many areas, once around 2% or so are known to be infected, herd immunity appears to emerge and the disease disappears. (2x10 = 20% actually infected) + 50% background immunity = 70%. Voila!

Nailed It!

 

[kiddiedoc]

So, three quick hits from office experience today:
1. According to a nurse at a local hospital, approx 50% of their admissions right now are vaccinated
2. At another local hospital, 5/7 of their CV deaths had been vaccinated
3. Monoclonal antibody use at local ERs is virtually non-existent. This is amazing and inexcusable. At least half of their CV+ patients are likely candidates for treatment, and it's literally the ONLY available treatment that we know prevents severe disease progression. I am digging for answers.

 

[kiddiedoc]

Just a reminder, since the troll is on a real mission today: we WERE at herd immunity.

New strain with significantly higher transmissibility and vaccine escape = higher HIT. Just clarifying, as I know that some people (apparently) don't understand immunology/epidemiology.

The question now is whether or not we can actually include vaccinated people into the herd immunity equation. If Pfizer protection is only, say 60%, that changes things significantly.

 

[volinbham]

Nailed It!

Delta has changed things as shown below.

Harvard epidemiologist Michael Mina told me in the long interview that follows below. “If this was still Alpha, sure. But with Delta, plenty of people are getting sick. Plenty of transmission is going on. And my personal opinion is that the whole notion of herd immunity from two vaccine shots is flying out the window very quickly with this new variant.”

“We’re seeing a lot more spread in vaccinated people,” agreed Scripps’s Eric Topol, who estimated that the vaccines’ efficacy against symptomatic transmission, which he estimated to be 90 percent or above for the wild-type strain and all previous variants, had fallen to about 60 percent for Delta. “That’s a big drop.” Later, he suggested it might have fallen to 50 percent, and that new data about to be published in the U.S. would suggest an even lower rate. On Wednesday, a large pre-print study published by the Mayo clinic suggested the efficacy against infection had fallen as far as 42 percent.

According to those leaked CDC documents, there were, as of late last month, 35,000 symptomatic breakthrough cases being recorded each week — about 10 percent of the country’s total. Presumably many more breakthrough cases were asymptomatic, which would drive the share up further.

But the piecemeal data does begin to tell you something, suggesting that breakthrough cases represent a bigger share of disease spread, particularly in the ongoing Delta wave, than has been widely acknowledged — perhaps, overall, somewhere in the range of 5 to 20 percent of current cases, rather than the 0 to 5 percent range. When I ran these figures by Topol, he said, “I think the numbers are right on, and I think they’ve clearly been getting worse as Delta became fully dominant, now approaching 100 percent of all U.S. infections.”

https://nymag.com/intelligencer/2021/08/breakthrough-covid-19-cases-may-be-a-bigger-problem.html

 

[Matt2496]

They really are terrified of this dude

It’s so obvious what they’re doing and it’s sickening

 

[SpaceCoastVol]

Replace "unvaxxed" with "fat" and I'm listening.

or smokers... or vapers.... or alcoholics....

 

[kiddiedoc]

Delta has changed things as shown below.

Harvard epidemiologist Michael Mina told me in the long interview that follows below. “If this was still Alpha, sure. But with Delta, plenty of people are getting sick. Plenty of transmission is going on. And my personal opinion is that the whole notion of herd immunity from two vaccine shots is flying out the window very quickly with this new variant.”

“We’re seeing a lot more spread in vaccinated people,” agreed Scripps’s Eric Topol, who estimated that the vaccines’ efficacy against symptomatic transmission, which he estimated to be 90 percent or above for the wild-type strain and all previous variants, had fallen to about 60 percent for Delta. “That’s a big drop.” Later, he suggested it might have fallen to 50 percent, and that new data about to be published in the U.S. would suggest an even lower rate. On Wednesday, a large pre-print study published by the Mayo clinic suggested the efficacy against infection had fallen as far as 42 percent.

According to those leaked CDC documents, there were, as of late last month, 35,000 symptomatic breakthrough cases being recorded each week — about 10 percent of the country’s total. Presumably many more breakthrough cases were asymptomatic, which would drive the share up further.

But the piecemeal data does begin to tell you something, suggesting that breakthrough cases represent a bigger share of disease spread, particularly in the ongoing Delta wave, than has been widely acknowledged — perhaps, overall, somewhere in the range of 5 to 20 percent of current cases, rather than the 0 to 5 percent range. When I ran these figures by Topol, he said, “I think the numbers are right on, and I think they’ve clearly been getting worse as Delta became fully dominant, now approaching 100 percent of all U.S. infections.”

https://nymag.com/intelligencer/2021/08/breakthrough-covid-19-cases-may-be-a-bigger-problem.html

Nailed it!

 

[SpaceCoastVol]

What is happening to this country?

 

[evillawyer]

Delta has changed things as shown below.

Harvard epidemiologist Michael Mina told me in the long interview that follows below. “If this was still Alpha, sure. But with Delta, plenty of people are getting sick. Plenty of transmission is going on. And my personal opinion is that the whole notion of herd immunity from two vaccine shots is flying out the window very quickly with this new variant.”

“We’re seeing a lot more spread in vaccinated people,” agreed Scripps’s Eric Topol, who estimated that the vaccines’ efficacy against symptomatic transmission, which he estimated to be 90 percent or above for the wild-type strain and all previous variants, had fallen to about 60 percent for Delta. “That’s a big drop.” Later, he suggested it might have fallen to 50 percent, and that new data about to be published in the U.S. would suggest an even lower rate. On Wednesday, a large pre-print study published by the Mayo clinic suggested the efficacy against infection had fallen as far as 42 percent.

According to those leaked CDC documents, there were, as of late last month, 35,000 symptomatic breakthrough cases being recorded each week — about 10 percent of the country’s total. Presumably many more breakthrough cases were asymptomatic, which would drive the share up further.

But the piecemeal data does begin to tell you something, suggesting that breakthrough cases represent a bigger share of disease spread, particularly in the ongoing Delta wave, than has been widely acknowledged — perhaps, overall, somewhere in the range of 5 to 20 percent of current cases, rather than the 0 to 5 percent range. When I ran these figures by Topol, he said, “I think the numbers are right on, and I think they’ve clearly been getting worse as Delta became fully dominant, now approaching 100 percent of all U.S. infections.”

https://nymag.com/intelligencer/2021/08/breakthrough-covid-19-cases-may-be-a-bigger-problem.html

https://www.nejm.org/doi/full/10.1056/NEJMoa2108891

88% effectiveness for Pfizer

With the BNT162b2 vaccine, the effectiveness of two doses was 93.7% (95% CI, 91.6 to 95.3) among persons with the alpha variant and 88.0% (95% CI, 85.3 to 90.1) among those with the delta variant. With the ChAdOx1 nCoV-19 vaccine, the effectiveness of two doses was 74.5% (95% CI, 68.4 to 79.4) among persons with the alpha variant and 67.0% (95% CI, 61.3 to 71.8) among those with the delta variant.

 

[NorthDallas40]

https://www.nejm.org/doi/full/10.1056/NEJMoa2108891

Silly ass troll

 

[evillawyer]

Silly ass troll

View attachment 386502

Yes, a new article from the New England Journal of Medicine is digging myself in a hole. Back to the kiddie table with you. The adults are talking.

 

[kiddiedoc]

1. It's too damn bad all these people in the hospital didn't read the UK NEJM study

2. Novavax is not used in the U.S.

 

[kiddiedoc]

Comparison of two highly-effective mRNA vaccines for COVID-19 during periods of Alpha and Delta variant prevalence

This is a large U.S. study with matched groups for age, sex, race, and prior hx of CV.

in July, the effectiveness against infection was considerably lower for mRNA-1273 (76%, 95% CI: 58-87%) with an even more pronounced reduction in effectiveness for BNT162b2 (42%, 95% CI: 13-62%). Notably, the Delta variant prevalence in Minnesota increased from 0.7% in May to over 70% in July whereas the Alpha variant prevalence decreased from 85% to 13% over the same time period.

 

[NorthDallas40]

Yes, a new article from the New England Journal of Medicine is digging myself in a hole. Back to the kiddie table with you. The adults are talking.

If by adult “you” mean disingenuous fool completely misrepresenting the state which is what you are doing then sure. I guess this stupidity is your next cued up hill to die on. Carry on!

 

[NorthDallas40]

1. It's too damn bad all these people in the hospital didn't read the UK NEJM study

2. Novavax is not used in the U.S.

Comparison of two highly-effective mRNA vaccines for COVID-19 during periods of Alpha and Delta variant prevalence

What the hell do you think you are some kind of practicing medical professional like a doctor?! The paralegal has spoken!

 

[VolnJC]

Just a reminder, since the troll is on a real mission today: we WERE at herd immunity.

New strain with significantly higher transmissibility and vaccine escape = higher HIT. Just clarifying, as I know that some people (apparently) don't understand immunology/epidemiology.

The question now is whether or not we can actually include vaccinated people into the herd immunity equation. If Pfizer protection is only, say 60%, that changes things significantly.

That posting box is closing in on her...she can't defend Biden on anything from immigration to economy so she has become a broken Chatty Cathy doll that only has one saying left "DeathSantis"

 

[TN Ribs]

They really are terrified of this dude

Terrified of his stupidity, as well they should be. This moron is literally ignoring common sense public health measures to score political points. He's as depraved as his idol Trump.

 

[NorthDallas40]

Terrified of his stupidity, as well they should be. This moron is literally ignoring common sense public health measures to score political points. He's as depraved as his idol Trump.

The DNC appreciates you taking a shift at water carrying and shilling in the preemptive attack on DeSantis.

 

[NorthDallas40]

1. It's too damn bad all these people in the hospital didn't read the UK NEJM study

2. Novavax is not used in the U.S.

Whoopsie @evillawyer !!

You really should read stuff before you post it.

 

[Carl Pickens]

Phil Valentine talked his doctor into prescribing Ivermectin, and he's been on a ventilator for over a week.

Ivermectin wasn’t the first treatment option. Don’t go all liberal BS on this

 

[evillawyer]

Whoopsie @evillawyer !!

You really should read stuff before you post it.

Where did I claim it was? I linked the article, pointed out the 88% effective rate for Pfizer, and then provided the direct quote from the paper that said that.

Back to the short bus with you!