I have one with over 110K miles and not a single problem to date and it gets good gas mileage. I have a first generation one with the Bose system and all the bells and whistles you could get in 2007. Its not bad. It has a CVT transmission which took a bit of getting used to for me at least. Its sometimes a bit jittery and slugish in the acceleration but its only 170hp 2.5L so..again mine is 1st gen 2008 model. Im sure the new ones have a redesigned interior.
I wouldnt buy another one though I need a bigger vehicle and I want something with a more power stock sound system, USB.microSD slots, ventilated seats, a v8 and a dimming outside driver mirror. To be honest I've never liked the way it looked. When I went to buy it I was actually looking for a Pathfinder. But gas prices had skyrocketed and the Nissan dealer hid the Pathfinders in the back lot. They pushed me towards the smaller ones.
Again, its not bad for a family with small kids..but squeezing 5 adults into is a pain. And the stupid oval design made it impossible for me to get a friggin 40" tv into the back.