Tampa is world renowned for its gentlemens clubs. Actually, Dale Mabry is not the only strip where the talent is strong in Tampa. We have a Hard Rock Casino too if that's your thing. Steak houses here are tops too.
In 2011 I traveled and stayed in Gainesville even though I live in Tampa. The people arent all that bad. Good hotels right off of 75. Any time you start hanging around the frat area, you should already expect idiocy.
Outside of the stadium and even in, most folks are cool. Most welcomed us, others you just walk away.
All that said, if you wanna make it a long weekend, some of the top rated beaches are in the Tampa area and the weather here is hot enough to enjoy them. Summer rain showers are done by September too.
Tampa is only 2 hrs from Gainesville, so it is really your call on if you want to drive after a game. If you have never been to the swamp you will likely be exhausted after the game due to the heat and humidity. It truly is a whole nother animal down here.
Bring sunscreen, glasses and a fan. hydrate