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Prior COVID Infection Doesn't Guarantee Good Immunity: Study

"Many people, and many doctors, are assuming that any prior exposure to SARS-CoV-2 will confer immunity to reinfection. Based on this logic, some people with prior exposure don't think they need to get vaccinated. Or if they do get vaccinated, they think that they only need the first dose of the two-dose Pfizer/Moderna vaccines," McDade said in a university news release.

"Our study shows that prior exposure to SARS-CoV-2 does not guarantee a high level of antibodies, nor does it guarantee a robust antibody response to the first vaccine dose," he said. "For people who had mild or asymptomatic infections, their antibody response to vaccination is essentially the same as it is for people who have not been previously exposed."

Study is antibodies, headline is immunity. Terrible, intentional I would assume.

But hey, it was 27 samples. Wow.
 
I think we all got COVID in my house. The nanny's Mom has it and the nanny has symptoms. 3 YO is asymptomatic. 7-month baby got it first in our group and has had cold symptoms but was clearly on the mend by day 3. My wife (she's getting tested today) has cold symptoms and I feel like I have minor allergies.

Update: I got pretty bad yesterday with allergy symptoms for a good portion of the day. Then by bedtime they were mostly gone and this morning I feel pretty good besides grogginess, but that's probably due to all the nyquill.

Wife isn't worse, but she's so over it. The baby hasn't really improved in a couple days, but that's OK because he barely seems sick. He's just a little more clingy and whiney than usual, otherwise we'd hardly notice it.
 
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Prior COVID Infection Doesn't Guarantee Good Immunity: Study

"Many people, and many doctors, are assuming that any prior exposure to SARS-CoV-2 will confer immunity to reinfection. Based on this logic, some people with prior exposure don't think they need to get vaccinated. Or if they do get vaccinated, they think that they only need the first dose of the two-dose Pfizer/Moderna vaccines," McDade said in a university news release.

"Our study shows that prior exposure to SARS-CoV-2 does not guarantee a high level of antibodies, nor does it guarantee a robust antibody response to the first vaccine dose," he said. "For people who had mild or asymptomatic infections, their antibody response to vaccination is essentially the same as it is for people who have not been previously exposed."

Only 27 people in the total sample (a subset of which had prior infection). So we are dividing a subset of 27 into at least 2 groups (those who had Covid with little or mild symptoms and those who had stronger symptoms).

From the study:

Participants who were seropositive (n = 13) and seronegative (n = 14) prior to vaccination were included. Four seropositive individuals had PCR confirmed COVID-19 infections; remaining seropositive individuals had asymptomatic cases.

They use confirmed PCR test as a proxy for severity of symptoms.

It seems the conclusion is that the vax illicits a stronger immune response for those who had symptomatic cases of Covid rather than concluding that having a mild case doesn't provide immunity.

"we find stronger vaccine responses following prior PCR-positive SARS-CoV-2 infection. Importantly, these stronger responses were limited to participants with PCR confirmed cases of COVID-19, and were not seen among those who did not experience symptoms or were seronegative."
 
Update: I got pretty bad yesterday with allergy symptoms for a good portion of the day. Then by bedtime they were mostly gone and this morning I feel pretty good besides grogginess, but that's probably due to all the nyquill.

Wife isn't worse, but she's so over it. The baby hasn't really improved in a couple days, but that's OK because he barely seems sick. He's just a little more clingy and whiney than usual, otherwise we'd hardly notice it.

hope it passes quickly
 

🤮 Lmao!!

We have a policy not to have more than 2 new grads at one time together on the schedule for a reason. It takes a year to train a new grad to be an icu rn. That first 4 months they don’t count in staffing. You know why mad? They have a mentor to keep them from accidentally harming people. Like the new grad that thought precedex was keppra and dumped a whole bag into a pt in 15 minutes. His heart rate went from 90 to 32.
hahaha... bring on the new grads and safety of pts will tank. Wise nurses know this to be true, that tictok nurse has no clue what she’s talking about. Nor any idea how to sculpt eyebrows. Eee gads.
 
I don’t know that it would go away immediately, but I think it would definitely help it run its course a lot sooner.

I’m not seeing it. Even if it ran its course a lot sooner, I just don’t see this going away.

I would still like to know what “running its course” looks like and how we know we have finished the course. What is the finish line? Transmission rates, rolling averages, deaths, hospitalizations….what metric or metrics say “we are finally over this”.

Nobody is willing or able to put that mark on the wall. That tells me a lot of this is just generated drama to keep clicks, ratings, and welfare increases going

From the beginning I have said this is what it is. It is going to make people sick and kill others no matter what. That is a tragedy and sucks…but COVID is here to stay and we were always going to have to live with it.

I really think this fizzles out when people lose interest and something else generates higher ratings. Until then, vaccine and mask stories still generate clicks.
 
Our youngest hit 100.3 temp last night. Gave him some NyQuil and he woke up this morning drenched in sweat and feeling 100%.

I suspect COVID or something is making its way through the house but nobody is getting seriously sick.
 
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hope it passes quickly

Seems to be passing quickly. I guess we can credit the vaccine for that. I would've hoped it would protect us entirely, but I don't think we stood a chance. The nanny brought it here to our house all week, and then we found out Saturday, so it was an onslaught of germs.
 
🤮 Lmao!!

We have a policy not to have more than 2 new grads at one time together on the schedule for a reason. It takes a year to train a new grad to be an icu rn. That first 4 months they don’t count in staffing. You know why mad? They have a mentor to keep them from accidentally harming people. Like the new grad that thought precedex was keppra and dumped a whole bag into a pt in 15 minutes. His heart rate went from 90 to 32.
hahaha... bring on the new grads and safety of pts will tank. Wise nurses know this to be true, that tictok nurse has no clue what she’s talking about. Nor any idea how to sculpt eyebrows. Eee gads.
I’d take a vaccinated nurse with crappy eyebrows any day over an unvaccinated nurse. I care more about healthcare workers treating patients that understand science versus fashion.
 
I’m not seeing it. Even if it ran its course a lot sooner, I just don’t see this going away.

I would still like to know what “running its course” looks like and how we know we have finished the course. What is the finish line? Transmission rates, rolling averages, deaths, hospitalizations….what metric or metrics say “we are finally over this”.

Nobody is willing or able to put that mark on the wall. That tells me a lot of this is just generated drama to keep clicks, ratings, and welfare increases going

From the beginning I have said this is what it is. It is going to make people sick and kill others no matter what. That is a tragedy and sucks…but COVID is here to stay and we were always going to have to live with it.

I really think this fizzles out when people lose interest and something else generates higher ratings. Until then, vaccine and mask stories still generate clicks.
We have crossed a threshold. The toothpaste is out of the tube. Cold and Flu season will have "mask advisories" every year. Covid season will see the same. As a cynic, I look at where we are and can't help but think the CDC long admired Asian countries and the masking the people do. They preplanned the next opportunity which presents in America to advance us towards the same behaviors.
 
We have crossed a threshold. The toothpaste is out of the tube. Cold and Flu season will have "mask advisories" every year. Covid season will see the same. As a cynic, I look at where we are and can't help but think the CDC long admired Asian countries and the masking the people do. They preplanned the next opportunity which presents in America to advance us towards the same behaviors.

I fear you are right. For those of us with ones in school, this has and will continue harm them from a developmental point of view.
 
I fear you are right. For those of us with ones in school, this has and will continue harm them from a developmental point of view.
With the way we approach it, I agree. Masked children attending school where masking is cultural are well-adjusted, I think.
 
Have to make decisions off that. I already pulled 1 to home school. Probably pulling the other 1 to that next year.
We were going to private school this year anyway. But the school we applied and were accepted are turning kids away due to capacity. 1st time in their 40+ year history.
 
We were going to private school this year anyway. But the school we applied and were accepted are turning kids away due to capacity. 1st time in their 40+ year history.

Yea, private schools are growing like crazy since this all started. Home schooling is also booming.

No skin off my back. I've criticized public schools for a long time, so now I am acting. Lemons to lemonade.
 
I’m talking from a virtual, mandated quarantining protocol perspective. I have one right now that can’t go back to school until a week from this Friday.
Yep. The way America does it is completely jacked up. If remote/virtual is here to say, I expect to see remote learning cooperatives sprout up. Places where parents can take their kids to remote learn AND interact with other kids.
 
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All Hail Science™

Amherst College Orders Vaccinated Students To Be Double-Masked Indoors

Amherst College in Massachusetts is welcoming students back to campus by implementing some of the most restrictive COVID-19 mitigation efforts anywhere in the country. Administrators will now require students to wear two masks while indoors, get tested every other week, eschew large social interactions, and generally refrain from leaving school grounds.

Amherst was already requiring all students and staff to be vaccinated, and less than 1 percent of the campus had sought any sort of waiver from this requirement.

But the college is going much further. Students will be required to wear not one but two masks while indoors. (If the mask is a KN95, then just one mask is allowed.) This policy actually contradicts CDC guidance, which recommends against people wearing multiple disposable masks at the same time.

Unmasking is only permitted while students are within their own dormitory rooms. There is no exception for eating in the cafeterias, since the cafeterias will all be closed: Amherst is canceling dining services for the time being. Students should definitely not think about going out to eat: Visiting bars and restaurants is strictly prohibited.
 
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