Looking at Charlie Creme's current projected 4 seeds, we'd be favored over all of them on a neutral court (per HHS), which is kind of why homecourt advantage for anyone in these early rounds is sucky. That said, we'd be favored to beat UNC or UCLA on the road (even though UCLA beat us this year on a neutral court), whereas we'd be projected to lose to Villanova by 3 on the road or beat them by 5 at home.
If we're a 5, the only 12 I really wouldn't want is South Dakota State. We're only projected to beat them by 2 on a neutral court, whereas we'd be a 9 point favorite over Toledo or 14 points over West Virginia/St. John's.