And you guys really put blind faith in Fauci?

#177
#177
Septic said:
Bro I think Biden, Trump, antifa, proud joys, BLM and oath keepers are idiots. But I don't have the gall to question any of thier American-ism. They all believe what they are doing or believe is best, right or wrong. What they have in common is thier patriotism.

Watching you attempt to gatekeep what it is to be an "American" is clownish. Consider looking in the mirror when evaulatung what's "tearing it apart" instead of pinning the problems we face strictly on those that don't see the world through your warped prism.
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I agree with you on one point. They are all idiots. However, BLM and Antifa have been physically destroying the country right in front of our eyes and no one is doing anything about it. But the left seem fine with that. What they have a problem with is people like me that can’t wait to see it come to my neck of the woods. Because of that fact, I put the proud boys in a lesser classification of “idiot” because someone needs to stand up. It’s only a matter of time before them or another created militia square off with them and my guess is what I’ve been saying all along. It’ll happen when BLM or Antifa grow a set and venture into unfamiliar territory outside of democratic cities. Saying you “don’t have the gall to question their patriotism” is plain out asinine. A patriot would never destroy his country or his city. Therefore BLM and Antifa are not patriots. In fact it’s pretty obvious they are the very definition of domestic terrorist.

I don’t need to look in the mirror. Obviously this country means more to me than it does to a lot on your side. My entire stance in any thread has been about freedom, anti tyranny and the right to defend myself, my family and my country from being forced to live the leftist point of view. It ain’t happening.
 
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#180
#180
1vol8 said:
I agree with you on one point. They are all idiots. However, BLM and Antifa have been physically destroying the country right in front of our eyes and no one is doing anything about it. But the left seem fine with that. What they have a problem with is people like me that can’t wait to see it come to my neck of the woods. Because of that fact, I put the proud boys in a lesser classification of “idiot” because someone needs to stand up. It’s only a matter of time before them or another created militia square off with them and my guess is what I’ve been saying all along. It’ll happen when BLM or Antifa grow a set and venture into unfamiliar territory outside of democratic cities. Saying you “don’t have the gall to question their patriotism” is plain out asinine. A patriot would never destroy his country or his city. Therefore BLM and Antifa are not patriots. In fact it’s pretty obvious they are the very definition of domestic terrorist.

I don’t need to look in the mirror. Obviously this country means more to me than it does to a lot on your side. My entire stance in any thread has been about freedom, anti tyranny and the right to defend myself, my family and my country from being forced to live the leftist point of view. It ain’t happening.
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Tl;dr

My guess is you disagreed and shored up your dumb take with more gatekeeping of whatever you've decided that makes an American a "patriot." Yawn.
 
#181
#181
Septic said:
Tl;dr

My guess is you disagreed and shored up your dumb take with more gatekeeping of whatever you've decided that makes an American a "patriot." Yawn.
Click to expand...
You can see it your way or you can remember my stance all along and stop wondering why I’m questioning the lefts “patriotism”. BLM don’t fall under the definition. Antifa doesn’t either. Judging by your comments in the past, you have a lot left to be desired yourself. But you know who does fall under the definition of “patriot”? Myself and the proud boys and if I’m the gate keeper, most democrats are on the outside looking in.
1BFE2E09-6AE0-41CA-94DB-CBC7A710A1B1.png
Just thought I would help you since you so obviously don’t know the true meaning of a patriot to determine one way or another.
 
#182
#182
1vol8 said:
I agree with you on one point. They are all idiots. However, BLM and Antifa have been physically destroying the country right in front of our eyes and no one is doing anything about it. But the left seem fine with that. What they have a problem with is people like me that can’t wait to see it come to my neck of the woods. Because of that fact, I put the proud boys in a lesser classification of “idiot” because someone needs to stand up. It’s only a matter of time before them or another created militia square off with them and my guess is what I’ve been saying all along. It’ll happen when BLM or Antifa grow a set and venture into unfamiliar territory outside of democratic cities. Saying you “don’t have the gall to question their patriotism” is plain out asinine. A patriot would never destroy his country or his city. Therefore BLM and Antifa are not patriots. In fact it’s pretty obvious they are the very definition of domestic terrorist.

I don’t need to look in the mirror. Obviously this country means more to me than it does to a lot on your side. My entire stance in any thread has been about freedom, anti tyranny and the right to defend myself, my family and my country from being forced to live the leftist point of view. It ain’t happening.
Click to expand...

You are entertaining if nothing else.
 
#184
#184
1vol8 said:
You can see it your way or you can remember my stance all along and stop wondering why I’m questioning the lefts “patriotism”. BLM don’t fall under the definition. Antifa doesn’t either. Judging by your comments in the past, you have a lot left to be desired yourself. But you know who does fall under the definition of “patriot”? Myself and the proud boys and if I’m the gate keeper, most democrats are on the outside looking in.

Just thought I would help you since you so obviously don’t know the true meaning of a patriot to determine one way or another.
Click to expand...

It's pretty clear that while you may have read my post about your opinions be a worthless measure of patriotism and how dumb you look trying to gatekeep, you didn't actually understand the post.
 
#186
#186
Septic said:
It's pretty clear that while you may have read my post about your opinions be a worthless measure of patriotism and how dumb you look trying to gatekeep, you didn't actually understand the post.
Click to expand...
If you meant it any other way than the way I took it, you failed on your delivery.
 
#190
#190
1vol8 said:
Thankfully? I bet every one of the dead soldiers that died defending what IS America would disagree.
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Are you going to speak for the vets or dead soldiers now too? You get to decide what they think as well? There are vets on every part of the political spectrum, including in these very forums - we may not always (or ever agree) on the best way for America to move forward, but we all damn sure are pulling for it go that way.

For you to decide who gets to wear the title of American or who is otherwise patriotic makes you look like a complete buffoon.
 
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#191
#191
Septic said:
Good, I'm for GOF research. I think it's smart to get out ahead of these - I do not think it's smart to do this in collaboration with an adversary.
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Interesting. What benefits derived from GOF research are most beneficial?

Honest question - seems like a difficult topic to simply Google
 
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#192
#192
85SugarVol said:
Interesting. What benefits derived from GOF research are most beneficial?

Honest question - seems like a difficult topic to simply Google
Click to expand...

Despite the ongoing debate, plenty of studies have imparted new functions to viruses, with clear benefit to science and medicine. Since the time when poliovirus was first grown in cultured cells, scientists have adapted viruses to live in culture. This enables production of a large supply of viral material for further study or for vaccine development. This process sometimes diminishes the pathogens’ ability to make humans ill. After all, the lab dish contains no immune system, so viruses can streamline their life cycles by dumping costly activities that would normally protect them from host attack, says Stanley Perlman, a physician and virologist at the University of Iowa in Iowa City.

Scientists have also directly modified viruses to create vaccines; the COVID-19 shots from both Oxford–AstraZeneca and Johnson & Johnson are based on adenoviruses harmless to humans that were modified to produce the SARS-CoV-2 spike protein. Researchers have also altered viruses to deliver gene therapies or cancer treatments. “All that great stuff that is going to benefit humanity is a gain of function,” says Vincent Racaniello, a virologist at Columbia University in New York City.

In addition, scientists routinely give viruses the ability to infect new hosts. Animal research — although fraught with its own set of ethical quandaries — allows scientists to study how pathogens work and to test potential treatments, a necessary precursor to trials in people. That’s what Perlman and his collaborators had in mind when they set out to study the coronavirus responsible for Middle East Respiratory Syndrome (MERS-CoV), which emerged as a human pathogen in 2012. They wanted to use mice, but mice can’t catch MERS.

The rodents lack the right version of the protein DPP4, which MERS-CoV uses to gain entry to cells. So, the team altered the mice, giving them a human-like version of the gene for DPP4. The virus could now infect the humanized mice, but there was another problem: even when infected, the mice didn’t get very ill. “Having a model of mild disease isn’t particularly helpful to understand why people get so sick,” says collaborator Paul McCray, a paediatric pulmonologist also at the University of Iowa.

So, the group used a classic technique called ‘passaging’ to enhance virulence. The researchers infected a couple of mice, gave the virus two days to take hold, and then transferred some of the infected lung tissue into another pair of mice. They did this repeatedly — 30 times9. By the end of two months, the virus had evolved to replicate better in mouse cells. In so doing, it made the mice more ill; a high dose was deadly, says McCray. That’s GOF of a sort because the virus became better at causing disease. But adapting a pathogen to one animal in this way often limits its ability to infect others, says Andrew Pekosz, a virologist at the Bloomberg School of Public Health.

The experiments did make the virus amenable to research, however, and the team shared both it and the engineered mice with others. It led to plenty of new findings. For example, Perlman’s team discovered that an immune-system protein called interferon fights the virus, at least in a very specific time window10. This parallels responses in people with SARS-CoV-2, suggesting that if interferon is provided as a treatment, it should be early in the course of the disease11.

Researchers also used the mouse-adapted MERS-CoV to test new vaccines and treatments. The Iowa team’s collaborators tested a vaccine that is a hybrid of parainfluenza virus with the MERS-CoV version of the spike. The vaccine wasn’t very effective when injected, but it did protect DPP4-expressing mice from MERS-CoV quite well when provided through the nose12. Although MERS outbreaks haven’t led to sustained transmission, this information has proved valuable in the COVID‑19 pandemic: a vaccine with the same design, but against the SARS-CoV-2 spike, works in mice and ferrets13 and is now undergoing early clinical trials. - Source: The shifting sands of ‘gain-of-function’ research
 
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#193
#193
Septic said:
Are you going to speak for the vets or dead soldiers now too? You get to decide what they think as well? There are vets on every part of the political spectrum, including in these very forums - we may not always (or ever agree) on the best way for America to move forward, but we all damn sure are pulling for it go that way.

For you to decide who gets to wear the title of American or who is otherwise patriotic makes you look like a complete buffoon.
Click to expand...
Are you comprehending the conversation here? I’m arguing that many soldiers have died protecting us from evils around the world. But I have a hard time believing that those that did die would be happy with what they would see today and the pussification that’s become of American citizens if they had to fight for their freedom themselves because of tyranny from within. It’s sad that hogg is right. I am in the minority because so many these days wouldn’t. They would rather just comply
 
#194
#194
1vol8 said:
Are you comprehending the conversation here? I’m arguing that many soldiers have died protecting us from evils around the world. But I have a hard time believing that those that did die would be happy with what they would see today and the pussification that’s become of American citizens if they had to fight for their freedom themselves because of tyranny from within. It’s sad that hogg is right. I am in the minority because so many these days wouldn’t. They would rather just comply
Click to expand...

Other than the first few months or year of Afghanistan there hasn’t been a US soldier that’s died defending our freedom or from the evils of the world since WWII. They died because they were sent places we didn’t belong to fulfill the BS agenda of a POS politician and bureaucrats. They died because they maned up, did their jobs and didn’t let their buddies down. Don’t degrade their sacrifices by equating it with some BS propaganda of god, country, flag, mom and apple pie.
 
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#196
#196
Septic said:
Despite the ongoing debate, plenty of studies have imparted new functions to viruses, with clear benefit to science and medicine. Since the time when poliovirus was first grown in cultured cells, scientists have adapted viruses to live in culture. This enables production of a large supply of viral material for further study or for vaccine development. This process sometimes diminishes the pathogens’ ability to make humans ill. After all, the lab dish contains no immune system, so viruses can streamline their life cycles by dumping costly activities that would normally protect them from host attack, says Stanley Perlman, a physician and virologist at the University of Iowa in Iowa City.

Scientists have also directly modified viruses to create vaccines; the COVID-19 shots from both Oxford–AstraZeneca and Johnson & Johnson are based on adenoviruses harmless to humans that were modified to produce the SARS-CoV-2 spike protein. Researchers have also altered viruses to deliver gene therapies or cancer treatments. “All that great stuff that is going to benefit humanity is a gain of function,” says Vincent Racaniello, a virologist at Columbia University in New York City.

In addition, scientists routinely give viruses the ability to infect new hosts. Animal research — although fraught with its own set of ethical quandaries — allows scientists to study how pathogens work and to test potential treatments, a necessary precursor to trials in people. That’s what Perlman and his collaborators had in mind when they set out to study the coronavirus responsible for Middle East Respiratory Syndrome (MERS-CoV), which emerged as a human pathogen in 2012. They wanted to use mice, but mice can’t catch MERS.

The rodents lack the right version of the protein DPP4, which MERS-CoV uses to gain entry to cells. So, the team altered the mice, giving them a human-like version of the gene for DPP4. The virus could now infect the humanized mice, but there was another problem: even when infected, the mice didn’t get very ill. “Having a model of mild disease isn’t particularly helpful to understand why people get so sick,” says collaborator Paul McCray, a paediatric pulmonologist also at the University of Iowa.

So, the group used a classic technique called ‘passaging’ to enhance virulence. The researchers infected a couple of mice, gave the virus two days to take hold, and then transferred some of the infected lung tissue into another pair of mice. They did this repeatedly — 30 times9. By the end of two months, the virus had evolved to replicate better in mouse cells. In so doing, it made the mice more ill; a high dose was deadly, says McCray. That’s GOF of a sort because the virus became better at causing disease. But adapting a pathogen to one animal in this way often limits its ability to infect others, says Andrew Pekosz, a virologist at the Bloomberg School of Public Health.

The experiments did make the virus amenable to research, however, and the team shared both it and the engineered mice with others. It led to plenty of new findings. For example, Perlman’s team discovered that an immune-system protein called interferon fights the virus, at least in a very specific time window10. This parallels responses in people with SARS-CoV-2, suggesting that if interferon is provided as a treatment, it should be early in the course of the disease11.

Researchers also used the mouse-adapted MERS-CoV to test new vaccines and treatments. The Iowa team’s collaborators tested a vaccine that is a hybrid of parainfluenza virus with the MERS-CoV version of the spike. The vaccine wasn’t very effective when injected, but it did protect DPP4-expressing mice from MERS-CoV quite well when provided through the nose12. Although MERS outbreaks haven’t led to sustained transmission, this information has proved valuable in the COVID‑19 pandemic: a vaccine with the same design, but against the SARS-CoV-2 spike, works in mice and ferrets13 and is now undergoing early clinical trials. - Source: The shifting sands of ‘gain-of-function’ research
Click to expand...
Well, I like the sound of novel delivery mechanisms for gene therapy.

Tell those researchers to keep the windows closed.
 
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#197
#197
#198
#198
1vol8 said:
Are you comprehending the conversation here? I’m arguing that many soldiers have died protecting us from evils around the world. But I have a hard time believing that those that did die would be happy with what they would see today and the pussification that’s become of American citizens if they had to fight for their freedom themselves because of tyranny from within. It’s sad that hogg is right. I am in the minority because so many these days wouldn’t. They would rather just comply
Click to expand...

Sounds like you don't even understand the argument and why I'm mocking your dumb take.

You keep trying to convince us why your personal opinion is the only basis on which these "American" and "patriotic" labels can be applied.

Don't let me get in the way of you speaking for the dead though.
 
#199
#199
Septic said:
Sounds like you don't even understand the argument and why I'm mocking your dumb take.

You keep trying to convince us why your personal opinion is the only basis on which these "American" and "patriotic" labels can be applied.

Don't let me get in the way of you speaking for the dead though.
Click to expand...
It’s my opinion. This is a message board. You come here to read the opinion of others do you not? Bottom line is you and others are taking a defensive stance against someone that provided Webster’s dictionary definition of the word “Patriot” which has been the basis of every argument I’ve made. Simply put, you’re not a patriot if you have a problem with my stance. In fact, it’s clear that patriots annoy you and a few others.
 
#200
#200
1vol8 said:
It’s my opinion. This is a message board. You come here to read the opinion of others do you not? Bottom line is you and others are taking a defensive stance against someone that provided Webster’s dictionary definition of the word “Patriot” which has been the basis of every argument I’ve made. Simply put, you’re not a patriot if you have a problem with my stance. In fact, it’s clear that patriots annoy you and a few others.
Click to expand...

Who the heck gave you the right to define who is and isn't a patriot?
 
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