I hope this will put this debate to bed... tired of hearing this hyped as a wonder-drug by the right, just because Trump has aggressively touted it in his press briefings.
From AP News (apnews.com):
More deaths, no benefit from malaria drug in VA virus study
By Marilynn Marchione April 21, 2020
(Excerpt)
A malaria drug widely touted by President Donald Trump for treating the new coronavirus showed no benefit in a large analysis of its use in U.S. veterans hospitals. There were more deaths among those given hydroxychloroquine versus standard care, researchers reported.
The nationwide study was not a rigorous experiment. But with 368 patients, it's the largest looks so far of hydroxychloroquine with or without the antibiotic azithromycin for COVID-19, which has killed more than 171,000 people as of Tuesday.
The study was posted on an online site for researchers and has not been reviewed by other scientists. Grants from the National Institutes of Health and the University of Virginia paid for the work.
Researchers analyzed medical records of 368 male veterans hospitalized with confirmed coronavirus infection at Veterans Health Administration medical centers who died or were discharged by April 11.
About 28% who were given hydroxychloroquine plus usual care died, versus 11% of those getting the drug plus azithromycin died too, but the difference between that group and usual care was not considered large enough to rule out other factors that have affected survival.
Hydroxychloroquine made no difference in the need for a breathing machine, either.
Researchers did not track side effects, but noted a hint that hydroxychloroquine might have damaged other organs. The drug has long been known to have potentially serious side effects, including altering the heartbeat in a way that could lead to sudden death....
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"What do you have to lose? It's been out there for a long time. What do you have to lose? I hope they use it." - President Donald Trump speaking to the White House press corps on Saturday April 4th, while encouraging coronavirus patients to take the unproven drug, hydrochloroquine, as a means of treatment.